A CoQ10 is generally well tolerated, even at extremely high doses of 1,000 mg per day or more .
However, some people who are sensitive to the compound may experience side effects, such as diarrhea, headache, nausea and skin rashes.
It should be noted that taking CoQ10 close to bedtime may cause insomnia in some people, so it’s best to take it in the morning or afternoon.
CoQ10 supplements can interact with some common medications, including blood thinners, antidepressants and chemotherapy drugs. Consult your doctor before taking supplemental CoQ10.
As it’s fat-soluble, those supplementing with CoQ10 should keep in mind that it’s better absorbed when taken with a meal or snack that contains a fat source.
Additionally, be sure to buy supplements that deliver CoQ10 in the form of ubiquinol, which is the most absorbable
